$HOME/Library/Containers/

contain the home directories of sandboxed apps that are for example the apps downloaded from the Mac App Store.

du -hs /Users/*/Library/Containers 2>/dev/null

rm -rf /Users/your-user/Library/Containers/*
rm: com.apple.CloudDocs.MobileDocumentsFileProvider: Operation not permitted
rm: com.apple.Notes: Operation not permitted
rm: com.apple.Safari: Operation not permitted
rm: com.apple.corerecents.recentsd/Data/Library/Recents: Operation not permitted
rm: com.apple.corerecents.recentsd/Data/Library: Operation not permitted
rm: com.apple.corerecents.recentsd/Data: Operation not permitted
rm: com.apple.corerecents.recentsd: Operation not permitted
rm: com.apple.mail: Operation not permitted
rm: com.apple.news: Operation not permitted
rm: com.apple.stocks: Operation not permitted

Related

• du -hs /Users/*/brew/

See also

• $HOME, ~/Library/, ~/Library/Containers/, ~/Library/Application Support/, ~/.local/